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The MDPI journal, Microorganisms, is ascientific journal with an esteemed reputation in the field of Microbiology. This journal has been indexed in SCIE for many years and has a high Impact Factor (IF=4.1 in 2023).

The novelty of iHA318® research and itssignificance to the healthcare industry are highly recognized by the journal. We are pleased and honored that the research findings on iHA318® have successfully passed the peer review and been published in the Microorganism journal. Please check the latest findings on iHA318® to stay tuned to the trends in the field of probiotics.
(https://www.mdpi.com/2076-2607/12/7/1306).

Percheron is honored to be featured in an interview with Technical Journal on Food Chemistry & Chemical, a professional journal focused on the trends of functional foods and highly reputed in the food industry.

During the interview, we presented the results of our groundbreaking research, showcasing Deltatonin® Longan Flower Extract as a novel solution for improving insomnia, boosting daytime energy, and relieving anxiety and depression. The incredible health benefits of Deltatonin® have been verified through in vitro, animal studies, and human clinical trials, and the functions have been patented. We are proud and confident to propose Deltatonin® as a comprehensive, side-effect-free, and natural solution for improving circadian rhythm and mood.

The magazine, フードスタイル2 Food Style, is an esteemed media focuses on the latest studies on the relationship between food and human health, as well as keeping up with the latest trends in the Japanese health food industry.

Our patented, proprietary, science-backed probiotic strains, iHA318 and UA881, which are isolated from human breast milk, were proudly featured in an interview by ''フードスタイル2 Food Style'' due to their unique functions and efficacy, which have drawn significant attention from the editors. iHA318 is the first and only probiotic strains having the functions in relieving Dry Eye Syndrome and prevent corneal damage. UA881 is a versatile probiotic strain that can relieve hyperlipidemia, hypercholesteremia, and hyperuricemia. It can also inhibit inflammation and activate the antioxidant systems in humans.

iHA318 and UA881 have been honorably awarded ‘’2024 Scientific Frontiers’’ by The International Probiotics Association (IPA) due to their novelty and solid scientific validation. The probiotic strains have been patented in multiple countries and are produced in a well-reputed factory in Europe. We are confident that iHA318 and UA881 will make a significant impact in the Japanese health market.

Technical Journal on Food Chemistry & Chemical (フードケミカル 食品化工月刊), founded in 1985, is a must-read publication for developers of food and health products in Japan. It primarily reports on the latest health market trends, technologies, and food safety information from a perspective of professional point of view. It has a high reputation in the Japanese food industry.

Two of our proprietary, patented, and science-backed probiotic strains were honorably reported by the journal because of the novelty of their health benefits and solid scientific validation behind them. iHA318 can secrete massive amounts of sialic acid and hyaluronic acid to moisturize eyes and alleviate inflammation. Results of our human clinical study show that it is the first and only probiotic strain in the world to have the function of relieving Dry Eye Syndrome. Another probiotic strain, UA881, can aid cardiovascular health by reducing triacylglycerides (TG) and cholesterol in serum. Additionally, UA881 also degrades uric acid and purine nucleosides, thereby reducing the risk of hyperuricemia and gout.

The Taiwanese Society for Nutritional Psychiatry Research (TSNPR) is an authoritative research institute in Taiwan dedicated to the research and application of neuroscience and nutritional medicine. The Innovation Award for Brain Health Products is the prestigious annual grand prize aimed at recognizing and encouraging the brain-care products with exceptional quality, novelty, and creativity.

Deltatonin, the Longan Flower Extract, can activate Serotonin/Melatonin synthesis pathway, regulating circadian rhythm, and improving sleep quality. Deltatonin has been proven through scientific experiments to be a natural inducer of melatonin, offering a safe alternative to melatonin pills and sleeping pills. The unique function and significant efficacy of Deltatonin have been recognized by the TSNPR, winning the Innovation Award for Brain Health Products.

The Probiota conference is the largest annual international congress in the field of probiotics, connecting the latest research between the industry and academia. In 2024, the probiota conference will be held in Milano from February 7th to 9th.

Percheron gladly announces that our innovative research on iHA318 and UA881 has been selected as 2024 Scientific Frontiers by the scientific committee of Probiota conference. We will present our inspiring results and clinical studies during the event. We would be delighted if you could visit our poster and booth. Please feel free to contact us to receive a 15% discount code for the event.

This year, Percheron Bioceutical invited our partners to spend a different kind of Christmas by sending warmth and happiness to "Taichung City Welfare for the Disabled Association" and fulfilling Christmas wishes for physically and mentally disabled children. When we contacted the association, we learned that the children had not celebrated Christmas for 2 years because of the COVID-19 epidemic. Therefore, children highly anticipated the coming Christmas and to receive Christmas gifts. Thanks to the efforts of both Percheron and the association, we have created a very memorable Christmas together for the children.

The Percheron team recalled that when procuring gifts, many stores also donated gifts to children on their own initiative, hoping to make a small contribution to social welfare and to influence society with their own power and invite more people to contribute to social welfare and environmental conservation. This is a profound embodiment of higher value in corporate CSR practices.

Thank you all for joining us and listening to our presentation.

World Sleep Congress is the biggest international scientific conference in the field of sleep. In 2023, researchers from more than 70 countries are attending the conference in order to acquire the latest knowledge regarding the science of sleep.

Deltatonin has been verified through in-vitro, in-vivo, and clinical trials to be a natural solution for regulating the circadian rhythm by enhancing serotonin secretion during the daytime and boosting melatonin secretion at night.

The achievements of Deltatonin have received notable recognition from the scientific community and have been invited to present on-site at the 2023 World Sleep Congress in Rio de Janeiro.

Japan Design, Idea, and Invention Expo (JDIE) has been held for ten years, having a high reputation worldwide. Every year, dozens of countries and hundreds of innovative inventions compete at this invention exhibition. In 2023, JDIE was held between July 6^th to 8^th in Tokyo. Among all of the competitors, Percheron was awarded the Gold Medal and Platinum Medal for ‘’Breast Milk Probiotic UA881’’

UA881 is a versatile functional probiotic with the ability to produce valuable micro-nutrients such as glutathione and folic acid. Moreover, UA881 also shows potential in relieving gout. UA881 can efficiently degrade purine nucleosides and uric acid, as well as reduce inflammation. In summary, UA881 obtained prestigious honors at the JDIE because of its ability to consistently provide valuable nutrients and alleviate hyperuricemia.

Probiota Americas is a world congress organized by NutraIngredients and International Probiotic Association (IPA). Every year, they invite world-leading experts to present the latest scientific, technical, and market insights. NutraIngredient sand IPA are on the hunt for entrepreneurial consumer-facing, science or technology-based companies to join them at Probiota Americas. In the year 2023, iHA318 stands out among numerous works and has been selected as 2023 Scientific Frontiers through peer review. The work of iHA318 regard to relieve Dry Eye Syndrome and prevent corneal damage has been invited to present in Probiota Americas as a Poster.

Down syndrome features gene deficiency with Chromosome 21. It tends to lead to slow growth, mental retardation, and other complications in babies. Down syndrome babies teach colleagues throughout the Company how to make cookies from scratch. It helps boost these babies’ self-confidence and sense of achievement. Our staff also understands how these babies managed to live through their inherited condition so that they learn to be more understanding and reduce misunderstanding, demonstrate the power of love through actual action.

Businesses support the charity by attending the hands-on baking class and making purchases in the field. It helps break the stereotype about people with mental disabilities and witness the hard work and capabilities of Down syndrome babies. This is the indispensable value of corporate social responsibility. We thank the Down Syndrome Foundation, the instructor at the shop, the chef, and the No. 21 angels.

The International Society of Microbiota (ISM) is a scientific, non-profit-making organization, which is founded in 2013, and has a great reputation in the field of microbiology. The research of iHA318 has been noticed by ISM because iHA318 is the first probiotic strain discovered to have the abilities to relieve Dry Eye Syndrome and promote recovery of the cornea. The organization has selected iHA318 (THE POTENTIAL OF STREPTOCOCCUS THERMOPHILUS IHA318 ON HYALURONIC ACID PRODUCTION AND RELIEVING DRY EYE SYNDROME) as One of the Best Studies in 2023 and invited us to have an On-Stage Presentation at 10^th Targeting Microbiota World Congress at Venice, Italy.

2023 Vitafoods Europe is the annual event for introducing Functional Food and Ingredients.  The exhibition will be held in Switzerland from May 9^thto 11^th. Percheron will exhibit five innovative, patented high-end functional ingredients with distinct health benefits. Percheron owns excellent technical and academic resources.

As a leading biotechnology company in Taiwan, we are committed to the research and development of high-end functional ingredients. Attending Vitafoods Europe 2023 is an important step for Percheron to promote excellent ingredients to the international market. We will continue to devote ourselves to the research and development of innovative functional healthcare ingredients to bring more health benefits to the public.

# Deltatonin #iHA318 #UA881 #INSTABERRIES #ESSENPRUNE

Recently, Taiwan's longan flower is entering the harvest season. Percheron research team personally went to the place of raw materials and communicated with local farmers to understand the safety and stability of the source of raw materials!

The cultivation techniques and harvesting methods of Taiwanese longan flowers are very unique. Farmers use natural methods to plant. They are friendly to the environment, operate sustainably and making the quality of Taiwanese longan flowers extraordinary and stable. The production process of longan flower is (I) Shake (II) Sieve (III) Dry (IV) Sieve (V) Selection (VI) Inspection, which is complicated and needs to be highlycontrolled.

The team visited the place of raw materials and established a deep cooperative relationship with local farmers. In addition to ensuring the stability and safety of the source of longan flowers, the traceability of raw materials to the origin is our dedication to quality. The ability of longan flowers to ease emotions and calm the mind has been highly valued in the international market
due to their important benefits to humans.

Percheron Bioceutical knows to “take fromsociety and use for society” and looks at devotion to environmental protection and conservation as well as social benevolence as our mission and responsibility.

All staff at Percheron Bioceutical, filledwith passion, traveled all the way north. We arrived at the Xiaonanwan Organic Farm in Linkou, New Taipei City. Led by the farmers, we planted cabbage seedlings. Each of us rolled up our sleeves, bent down and toiled away.

Staff at Percheron Bioceutical serveschildren in orphanages in their own way, realize the importance of environmental protection and conservation, environmentally friendly agriculture, and the hard work of farmers during the process, and learn to be grateful and treasure what they have. We thank the joint efforts made by the Home-waiting Baby Association and the farmers.

The Moscow International Salon of Inventions and Innovative Technologies (Archimedes) was held between the 28^th and 30^th of March, 2023 in Russia. There were 110 competitive innovative inventions from multinational organizations that participated together. Among them, Percheron was awarded the gold medal and the TISIAS Special Award for "Breast Milk Probiotics iHA318.

iHA318 can produce valuable ingredients like HA and SA. Most importantly, iHA318 is able to increase tear secretion, maintain eye moisture and prevent corneal damage under UVB exposure. In summary, the edible probiotic S. thermophilus iHA318 has the potential to be an all-around strategy to relieve Dry Eye Syndrome and improve eye health.

The Moscow International Salon of Inventions and Innovative Technologies (Archimedes) was held between the 28^th and 30^thof March, 2023 in Russia. This exhibition gathered across broader competitions from 6 regions including Taiwan, Iran, Cambodia, China, Hong Kong, and Macau.

Percheron attended the competition “Relieving Dry Eye Symptoms by Breast Milk Probiotic iHA318”. iHA318 has been proved by animals and humans that iHA318 is rich in various health benefits and is safe and has no side effects. It is a new choice for maintaining consumers’ eye health.

Percheron and all of the lovely friendsdeparted from varying locations in Taiwan, heading to the “Natural Ecology educational Center of Changhua County" . Totally, more than a hundred of people on a sunny day hummed the thanksgiving song and worked very hard, picking up a lot of uncountable messy garbage.

Sustainability & Georgeous Sceneryin the World 

Wewitnessed the stunning quantities of plastics, straws, rubber bands… etc. as
the ocean wastes and garbage, which have already destroyed the ecology and food
chain of the ocean, whilst undoubtedly humans are on the top of the chain. It
is believed that the value of cherishing the oceans and the seas, caring for
resources sustainability, and safeguarding our next generations shall be passed
down to people in Taiwan. We will do itwithout question in the future.